Scientists have uncovered a powerful genetic switch that helps some of the body’s most important immune cells grow up properly and keep our organs healthy. The switch, called MafB, guides immature ...

A single genetic “switch” may be the secret to how the body’s cleanup crew grows up and keeps our organs running smoothly.

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs. The MafB factor, a veritable ...

The engineered organ has implications for everything from rapid production of immune therapies to new frontiers in cancer or infectious disease research. The immune organoid was created in the lab of ...

Organ transplants save lives, but unfortunately rejection is a key hurdle. Now scientists have demonstrated a potential new way to prime a recipient’s immune system to accept a transplanted organ, by ...

Modifying the organ instead of the recipient isn’t a new idea, but it is an important one, said Jeffrey Platt, a transplantation biologist at the University of Michigan Medical School who was not ...

Axolotls are famous for their ability to regrow significant parts of their bodies. But according to recent research, these frilly-headed salamanders, which are native to lakes and wetlands around ...

During fasting or exercise, immune cells (red) migrate to the pancreas and stimulate glucagon-producing cells (orange) to regulate blood sugar, with cell nuclei shown in blue. “For decades, immunology ...