The significant mortality rate associated with the ongoing Coronavirus disease 2019 (COVID-19) pandemic has been linked to acute respiratory distress syndrome (ARDS) and multi-organ dysfunction.

Mast cell activation syndrome (MCAS) is a condition that occurs when the mast cells in your body release too much of a substance that causes allergy-like symptoms. Mast cells are part of your immune ...

When our body requires defending from “non-self” entities, it deploys immune cells. This diverse group performs a wide variety of specialized functions to prevent us becoming ill. Mast cells have ...

Figure 1: Design of the HtTA and the HBI for the selective inhibition of mast cell degranulation. In this study, we developed a well-defined, multicomponent experimental system that enabled an ...

The mast cell has long been considered to be of paramount importance in the pathophysiology of asthma. Its key role in driving the IgE-mediated allergic reaction and thus the early asthmatic response ...

Inflammation is the body's response to harmful stimuli, characterized by heat, pain, redness, swelling, and loss of tissue function. When balanced, inflammation protects the body by clearing harmful ...

Mast cells have a long history in Freiburg. In the winter of 1876, medical student and later Nobel Laureate Paul Ehrlich discovered mast cells at the Institute of Anatomy in Freiburg. When ...

Mast cell activation syndrome is a condition that causes mast cells to release an inappropriate amount of chemicals into your body. This causes allergy symptoms and a wide range of other symptoms.