Researchers participating in the Enzyme Function Initiative (EFI) have used a computationally rich metabolite-docking strategy to sift through a protein’s potential metabolic partners and predict its ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

Enzymes help with specific functions that are vital to the operation and overall health of the body. They help speed up chemical reactions in the human body. They are essential for respiration, ...

Ancient enzymes, known for their fundamental role in translating genetic information into proteins, have evolved a myriad of other functions in humans, research shows. The surprising discovery ...

Many enzymes have non-canonical or non-enzymatic functions. Therefore, these enzymes can still be functional when their activity is compromised, such as after inhibition with an active site inhibitor ...

Doctors have long treated heart attacks, improved asthma symptoms and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

COLLEGE STATION, Nov. 6, 2007 – Fitting a key into a lock may seem like a simple task, but researchers at Texas A&M University are using a method that involves testing thousands of keys to unlock the ...

Synthetic biology is a growing field of research that is aiming to create a new kind of organism. Engineering synthetic proteins that can perform simple cellular functions as they would in real life ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. Researchers said the AI tool, ...