Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

We are starting to unpick the genetics of fibromyalgia, a poorly understood condition that causes chronic pain all over the body. The results of two studies – with millions of participants between ...

Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been ...

Parkinson’s disease is a complex neurodegenerative disorder. The causes are still unclear, but about 10% to 15% of cases are thought to be due to genetic changes, while exposure to certain things in ...

Certain rare genetic disorders may cause a child to develop obesity. Health experts may refer to these conditions as syndromic childhood obesity. They may affect a child’s metabolism or cause them to ...

Genes may play a bigger role in living a longer life, while lifestyle and luck still shape the outcome, according to a new ...

A large population-genetics study has revealed that people with ancestry from the Outer Hebrides, Northern Ireland and north-west Ireland face the highest risk of hereditary haemochromatosis, ...