Immunologists have identified a previously unrecognized group of immune cells that could reshape how vaccines and immune-based therapies are designed. The newly described cells 1 are long-lived memory ...

Study dissects HIV reservoir clones that persist on ART, revealing how CD8+ T cells and resistance pathways could be harnessed for future cure strategies.

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity. The ...

Study reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and effector function of CD4 T cells while reducing regulatory T cell suppression. Study: Subset-specific ...

Findings suggest engineered CD4+ T cells can modify Alzheimer's pathology and improve CNS immune responses, highlighting a ...

Treating inflammatory or autoimmune disorders in which the immune system overreacts and starts attacking the body can involve shutting down the whole immune system, and this may increase the risk of ...

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

Cancer immunotherapy has revolutionized treatment for many patients, but significant challenges remain in predicting who will respond to these life-saving treatments. A new comprehensive review ...